The advantage of being adjacent to Hong Kong and located in the Pearl River Delta Region which has an advanced manufacturing industry is to be exploited by Guangzhou to develop a new upgrading mode for modern service industry driven by service outsourcing.Guangzhou need to focus on cooperation with Hong Kong and fully use its international connecting channels to expand international service outsourcing market in terms of offshore outsourcing；to cultivate local leading enterprises with independent intellectual property and brand to enhance the competitiveness of local enterprises based on the Pearl River Delta market；to gradually promote the development of onshore outsourcing through offshore outsourcing to accelerate modern service industry development and upgrade in Guangzhou.