As the science and technology center in south China area，Guangzhou has put forward a series of policies on concentrating science and technology resources，improving independent innovation capability and promoting high-tech industries development，which shows great power in science and technology elements and talents concentration and science and technology radiation. The number of research institutes and research staff in Guangzhou is top of Pan-PRD，and Guangzhou enjoys a high degree of market orientation in science and technology allocation，but still under the ideal situation. At present，government’s policy instruction on improving the combination of the supply and demand of science and technology still need to be strengthened，keeping the three main bodies of government，enterprises and research institutes be ordinate by institutions，and bringing the function of operation main bodies into full play.