From the late 20th Century to the early 21st Century，a reversal of economic innovation and development direction has started to take place in some developed countries.Influencing power and driving power of culture on the economy have attracted great attention.Cultural Economy has been on the horizon.At present，capital，science & technology and the greed in market system have revealed the obvious lack of moral，ethical and aesthetic value.The future sustainable development of economy and society is in urgent need for culture.Meanwhile，cultural industries and creative industries are creating new growth engines in some countries，which grow in an exponential or explosive manner.Can cultural innovation system become another national strategy for boosting the future economic and social innovation and development？In view of new domestic and international trends，we must review significance and mission of cultural innovation and the construction of cultural innovation system.