Since the reform and opening-up，science and technology has been a main force that propels economic and social development，and innovation drive becomes an irresistible trend.The contemporary China has stepped into a new era of the integrative development of culture and science and technology.Based on this situation，this article systematically explores the innovation drive impelling the integration of culture and science and technology，and argues that scientific and technological progress is not only the driving force of cultural development but also the progressive form of cultural existence.The scientific and technological progress promotes the cultural innovation，as well as the breed and birth of “New Culture”.Current cultural construction should emphasize science and technology consciousness.