At present, integration of urban agglomeration in the middle reaches of the Yangtze River city is still in its infancy, especially industrial cooperation. Related to economic interests, although these cities have the strong willingness to cooperate, substantial progress is not significantly. In this paper, proposing three ways to accelerate the urban agglomerations industry of the middle reaches of the Yangtze River cooperation, on the basis of the systematic analysis of current situations and problems of industrial cooperation in this area. <<