Yuexiu District has leaded the development in such fields as original creation of animation，culture media，publishing exhibition & performances，creative design，circulation and consumption of creative derivatives，etc. it has become the core area of creative industry in Guangzhou. Starting from the business environment，business culture atmosphere，industry base，industry chain，industry profiles，economic indicators，spatial distribution and other aspects，this paper elaborates on the unique advantage and development situation of the creative industry and its development situation in Yuexiu District，sums up the main development methods，reveals its existing problems，proposes the development ideas，and makes forecast in improving the development layout，building key projects and service platform，optimizing the policies and measures，cultivating the leading enterprises，increasing the effort for intellectual property protection，and expanding the investment and financing channels and other aspects.