The creativity industry was the recent years emerging industry，it take the culture as the core，take the creativity as the driving influence，take the small scale，the personalization，the nimble production as the main form。The creativity industry and the old city have places of the many conjunction，the creativity industry needs the cultural resources，low cost’s undertaking place，the convenience life working condition may obtain in the old city，and the old city’s slack space uses again，industrial reforming，the image promotion to be possible again to realize through the creativity industry。Therefore，actuates the urban regeneration through the creativity industry’s development is practical and feasible and essential。This article has conducted the research take Guangzhou Liwan as the example to the creativity industry and the old city’s regeneration，thought that creativity industry’s and so on cultural traveling，characteristic trade，cultural art，design development have the important promotion effect regarding its urban renewal，at the same time，but also needs to complete the related necessary work，like strengthens to the traditional culture resources protection，provides the space，the building good housing，the undertaking environment for the creativity industry and so on.