The original idea of Guangzhou’s modern urban development strategy is to play Guangzhou’s bellwether role as are central city. After promoting by from spontaneous nongovernmental force to joint-enterprise，the relationship between Guangzhou and neighborhood areas is now pushed forward by both market and government，and also it faces certain problems such as challenge to Guangzhou’s central position，space division within area，evolution of industrial structure and economic development mode of district. For the sake of enhancing the leadership of Guangzhou as area central city，we shall focus on common benefits in area，and by combining intensive and extensive mode，through the aspects of factor，system，industry，distribution and cooperation，forge Pearl River Delta area to area economic group army.