In recent years，along with the rapid development of urbanization，there has been a series of urban sub-health problems to be solved. Therefore，establishing a systematic and scientific evaluation index system on urban healthy development has both theoretical and practical significance，further to guide and promoteurban development in a healthy way. Based on the idea to promote economic，social，cultural，ecological and management progress，this paper establishes an evaluation index system on urban healthy development and makes a comprehensive evaluation of 287 prefecture-level cities. The results point out four major features. Firstly，the level of healthy development in Chinese cities is generally low and the proportion of sub-health cities is large. Then，cities in east area have higher healthy development level，while in west area are lower. What’s more，the development gap among different provinces is obvious large. Third，large cities enjoy better healthy development but their ecological quality is bad. At last，the healthy development of medium-developed cities exhibits a relatively balanced state compared with the economically developed cities. In conclusion，the overall healthy development of Chinese cities is not optimistic；it is an urgent task to promote transition from sub-healthy to healthy development for all cities.