In this study，data related to 17 significant micro-blog public events are grabbed by data analysis software to filter out the Lead Disseminators in micro-blog discussion. This study analyzes the present situation characteristic and social responsibility of opinion leaders. The study found micro-blog opinion leaders，the social responsibility of the subject is mainly the social elite groups，social grassroots groups gradually marginalized. Micro-blog opinion leaders in social responsibility for the overall score is not high，especially the “education” function is not effective. To upgrade the overall level micro-blog opinion leaders in social responsibility，need to opinion leaders，the efforts of the government，network operators.