As the central cities of the Changjiang Middle Reaches Urban Agglomeration，Wuhan，Changsha，Nanchang and Hefei not only have good development foundation，but also much in common such as traffic and location，the domestic market，the ecological construction and the interest appeal. The four cities should stick to the point，jointly make a plan for the regional development，promote the cooperation in the self-dependent innovation and industry division，and work together to construct the regional transportation infrastructure，open market system，ecological civilization，as well as the culture-oriented tourism and public service sharing areas.