The worsening urban disease of Beijing has its deep cause in urban-rural relationship. The disjoint between population urbanization and space urbanization is an important incentive of urban disease. The rural-urban fringe zone which originated from the disjoint could be regarded as the typical zone of Beijing’s urban disease. Actually，besides the typical economic and technical measures，the amelioration of urban disease need also get help from rural zone. Since the mismatch of urban-rural relation will deteriorate urban disease，the integration of urban and rural could be a important solution for Beijing’s urban disease relief.