Guangzhou concentrates on the construction of national central city and regards the construction of powerful culture city and world cultural city as its main purpose. The report analyzes the cultural advantages and disadvantages of the construction of national central city of Guangzhou firstly, and then proposes to cut in cultural field with the cultural innovation management as is knob, encourages cultural participation and regional cooperation, improves industry integration, focuses on channel construction, expand the innovation class, emphasizes and regulates the construction of culture innovation cluster district, improves the construction of powerful culture city and world cultural city further. <<