The Yangtze River Economic Zone is the key area and growth axis of China’s economic and social development in the next 10 years. This report based on the great significance of the construction of the Yangtze River Economic Zone，the main basis，forecasting，analysis and forecast the transformation upgrade and strategic location，combined with field survey，to explore the opportunities and challenges facing the advantages and disadvantages of existing docking. For the Yangtze River Economic Zone construction，Anhui focuses on the strategic emphasis of function orientation，the role of Anhui in the Yangtze River Economic Zone development strategy，the industry in the regional division of labor cooperation relations，economic transformation and development，and how to create new regional growth poles and accelerates the transformation and upgrading of Wanjiang City belt and other issues，and proposes the corresponding countermeasure，policy measures and relevant recommendations accordingly.