Abstract：In this study，10 typical opinion leaders account for the case，analyzes the fulfillment of social responsibility of media practitioners micro-blog opinion leaders in the group. The study found that，the social responsibility of media practitioners overall opinion leaders in scoring in the mid to upper level. In the breakdown，media practitioners generally pay attention to the quality of information，so the information production responsibility score is high，cultural education and coordination responsibility score at a moderate level，the responsibility of social supervision with low scores. The key problem of the responsibility of governance is to strengthen top-level design and system construction，the protection of rights of media practitioners and clear its obligations，so that it can fulfill the social responsibility in the legal system，a healthy communication environment.