Industries with high scientific and/or technological content are very important for London’s economy. However，there has been no agreed statistical definition which in the UK Standard Industrial Classification can be categorized as having a significant “Science and Technology” content. A classification of ‘Science and Technology’ drawn up by the ONS London statisticians working with the GLA attempts to address this issue. It contains five sub-categories as follows：digital technologies；life sciences and healthcare；Publishing and broadcasting；other scientific/technological manufacture；and other scientific/technological services. Through applying this category we can find how employee jobs and workplaces change in science and technology in London and the boroughs，and map the spatial distribution of employment for London and Inner London.