Science and technology industrial park is an important policy tool to promote industrial upgrade and regional development. Each country or area would like to make efforts to develop various forms of industrial park based on its technology level, industrial structure and social economic conditions. The construction of Macau-Guangdong cooperative Chinese Medical Sci-Tech Industrial Park is a diversified economic development strategy put forward by Macau government, under the guidance of regional planning from the central government. Firstly, this article will analyze the reasons and the foundations that facilitated the Macau-Guangdong cooperation on Chinese Medical Sci-Tech Industrial Park, and then introduce the related development objectives and cooperation mode. Next, we will theoretically explore the development path of Chinese Medical Sci-Tech Industrial Park and put forward series of feasible strategies. Finally, we discussed its influences on economy and society of Macau. <<