With the increasingly close cooperation between the political and economic relations，the urgency for China and Central Asian countries to strengthen cooperation in the humanities is also increasing. Culture is the field of cooperation that started a bit late in relations between China and Central Asian countries. In recent years，China’s cooperation in education with Central Asian countries promoted the cultural cooperation，and further enhanced the quality and depth of cooperation. Exchanges and cooperation in science and technology，tourism，health and epidemic prevention is warming up and the scale and the quality of cooperation has also been a corresponding enhancement. In the background of the initiative proposed by the Silk Road Economic Zone，cultural cooperation will become the driving force for China and Central Asian countries to communicate with the common people.