In the construction of Maritime Silk Road in 21st Century，Guangzhou shall take its advantage to choose the key fields of development，such as foreign trade，cultural cooperation and overseas Chinese，on the basis of the national demands. Guangzhou shall seize the new challenge of foreign trade，the new pattern of cultural opening，and the new changes of overseas Chinese society，and strenghthen the degree of reform and innovation to take positive development measures on the strategic positioning of building the new business center，the culture center and the center of overseas Chinese on the Maritime Silk Road in 21^st Century.