Zhejiang qinghua Yangtze river delta research institute is the cooperative innovation mode of production, study and typical cases in China.Features based on the triple helix theory innovation, system research institute in the university - the government - industry "in the interactive cooperation" mode of the big dipper "-" industry-university-institute Jin Jieyong politics "model, and through the" campus bearing, achievements, finance, international cooperation of science and technology "the establishment of the four big platform effectively gather from colleges and universities, enterprises and intermediary agencies and other knowledge of human resources, effectively promoting the scientific and technological achievements of continuous innovation and rapid and efficient transformation, then the implementation of the benign innovation ecological system building process, the main interaction mechanism, the key success factors and typical patterns of innovation.Study found that zhejiang qinghua Yangtze delta institute based on the theory of triple helix innovation platform support the multi-factor model of development of best practice with strong representativeness and generalization, and deepen people's understanding of science and technology innovation and achievements transformation system, enrich the connotation of triple helix innovation theory and boundary.